Combine crumbs, sugar and butter. Press into bottom and sides of 10” spring form pan. Chill while preparing filling.
Blend cream cheese, sugar, flour, grated rinds and vanilla in large mixer bowl at high speed. Beat in eggs and yolks, one at a time, beat until smooth, scraping bowl with spatula. Beat in whipping cream. Pour over crust.
Bake at 500°F on bottom oven rack for 10 minutes. Lower oven temperature to 250°F and bake on middle oven rack for 60 minutes. Cool completely on wire rack. Serve at room temperature with your favourite topping.